LZTR1 Antibody
Product Specifications
Background
LZTR1 Antibody: LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
NCBI Gene ID
8216
Swiss Prot
Q8N653
Accession Number
CAJ86451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
LZTR1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1301 - Human Heart Tissue Lysate
Concentration
1 mg/mL
Buffer
LZTR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
LZTR1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5621
Fragment
IgG
Symbol
LZTR1
NCBI Official Name
Leucine-zipper-like transcription regulator 1
NCBI Organism
Homo sapiens
Background Reference 01
Kurahashi H, Akagi K, Inazawa J, et al. Isolation and characterization of a novel gene deleted in DiGeorge syndrome. Hum. Mol. Genet.1995; 4:541-9.
Background Reference 02
Nacak TG, Leptien K, Fellner D, et al. The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis. J. Biol. Chem.2006; 281:5065-71.
Other Product Names
LZTR1 Antibody: BTBD29, LZTR-1, SWNTS2, TCFL2, Leucine-zipper-like transcriptional regulator 1
Tested Applications
ELISA, WB, IHC-P
Protein ID
90403050
Physical Properties
Liquid
Available Sizes
Curated Selection
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