ARHGAP18 Antibody
Product Specifications
Background
ARHGAP18 Antibody: ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
NCBI Gene ID
93663
Swiss Prot
Q8N392
Accession Number
NP_277050
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
ARHGAP18 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Concentration
1 mg/mL
Buffer
ARHGAP18 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ARHGAP18 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
ARHGAP18
Positive Control 2
Cat. No. 17-201 - 3T3/BALB Cell Slide
NCBI Official Name
Rho GTPase activating protein 18
NCBI Organism
Homo sapiens
Background Reference 01
Takai Y, Sasaki T, and Matozaki T. Small GTP-binding proteins. Physiol. Rev.2001; 81:153-208.
Background Reference 02
Potkin SG, Turner JA, Fallon JA, et al. Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. Mol. Psychiatry2009; 14:416-28.
Other Product Names
ARHGAP18 Antibody: SENEX, MacGAP, bA307O14.2, Rho GTPase-activating protein 18
Tested Applications
ELISA, WB, ICC, IF
Protein ID
39932589
Physical Properties
Liquid
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
