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CHORDC1 Antibody

Product Specifications

Background

CHORDC1 Antibody: The cysteine and histidine-rich domain (CHORD) -containing protein (CHORDC1) is a member of a highly conserved protein family that contains the plant protein RAR1 and the mammalian protein melusin. In mammals, CHORDC1 is an ADP-dependent HSP90-interacting protein, and this interaction is dependent on the ability of HSP90 to bind nucleotides. Recent experiments indicate that CHORDC1 mRNA is diurnally regulated in mouse hypothalamus, and that this regulation alters during development, suggesting that CHORDC1 may play a role in circadian mechanisms in the mammalian brain.

NCBI Gene ID

26973

Swiss Prot

Q9UHD1

Accession Number

NP_036256

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

CHORDC1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Pig: (100%), Bovine: (100%), Chicken: (86%)

Buffer

CHORDC1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CHORDC1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=5587

Fragment

IgG

Symbol

CHORDC1

Positive Control 2

Cat. No. 17-010 - HEK293 Cell Slide

NCBI Official Name

Cysteine and histidine-rich domain (CHORD) -containing 1

NCBI Organism

Homo sapiens

Background Reference 01

Shirasu K, Lahaye T, Tan MW, et al. A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Cell1999; 99:355-66.

Background Reference 02

Brancaccio M, Menini N, Bongianni D, et al. Chp-1 and melusin, two CHORD containing proteins in vertebrates. FEBS Lett.2003; 551:47-52.

Background Reference 03

Wu J, Luo S, Jiang H, et al. Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein. FEBS Lett.2005; 579:421-6.

Background Reference 04

Gano JJ and Simon JA. A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. Mol. Cell Proteomics2010; 9:255-70.

Other Product Names

CHORDC1 Antibody: CHP1, CHP1, Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, CHORD-containing protein 1

Tested Applications

ELISA, WB, ICC, IF

Protein ID

221316566

Physical Properties

Liquid

Available Sizes

Curated Selection

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