NAT11 Antibody
Product Specifications
Background
NAT11 Antibody: N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE) . Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.
NCBI Gene ID
79829
Swiss Prot
Q86UY6
Accession Number
NP_079047
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
NAT11 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1314 - Human Thymus Tissue Lysate
Concentration
1 mg/mL
Buffer
NAT11 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NAT11 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5549
Fragment
IgG
Symbol
NAA40
NCBI Official Name
N (alpha) -acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Arnesen T, Van Damme P, Polevoda B, et al. Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proc. Natl. Acad. Sci. USA2009; 106:8157-62.
Background Reference 02
OK Song, Wang X, Waterborg JH, et al. An Nalpha-acetyl-transferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J. Biol. Chem.2003; 278:38109-1
Other Product Names
NAT11 Antibody: NAT11, PATT1, NAT11, N-alpha-acetyltransferase 40, N-acetyltransferase 11
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
189571650
Physical Properties
Liquid
Available Sizes
Curated Selection
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