FAM212A Antibody
Product Specifications
Background
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1) . FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1) . In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2) .
NCBI Gene ID
389119
Swiss Prot
Q96EL1
Accession Number
NP_976248
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell, Neuroscience
Purification
FAM212A antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1287 - EL4 Cell Lysate
Concentration
1 mg/mL
Buffer
FAM212A antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
FAM212A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.
Symbol
FAM212A
NCBI Official Name
Family with sequence similarity 212 member A
NCBI Organism
Homo sapiens
Background Reference 01
Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.
Background Reference 02
Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.
Other Product Names
Family with sequence similarity 212 member A, INKA1, C3orf54
Tested Applications
ELISA, WB
Protein ID
42766424
Physical Properties
Liquid
Available Sizes
Frequently Asked Questions
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