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FAM212A Antibody

Product Specifications

Background

FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1) . FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1) . In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2) .

NCBI Gene ID

389119

Swiss Prot

Q96EL1

Accession Number

NP_976248

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell, Neuroscience

Purification

FAM212A antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1287 - EL4 Cell Lysate

Concentration

1 mg/mL

Buffer

FAM212A antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

FAM212A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=5531

Fragment

IgG

Specificity

FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.

Symbol

FAM212A

NCBI Official Name

Family with sequence similarity 212 member A

NCBI Organism

Homo sapiens

Background Reference 01

Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.

Background Reference 02

Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.

Other Product Names

Family with sequence similarity 212 member A, INKA1, C3orf54

Tested Applications

ELISA, WB

Protein ID

42766424

Physical Properties

Liquid

Available Sizes

Curated Selection

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