FAM59B Antibody
Product Specifications
Background
FAM59B Antibody: FAM59B is related to the FAM59A protein (also known as GAREM) . While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
NCBI Gene ID
150946
Swiss Prot
Q75VX8
Accession Number
Q75VX8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
FAM59B Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1220 - SK-N-SH Cell Lysate
Concentration
1 mg/mL
Buffer
FAM59B Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
FAM59B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5481
Fragment
IgG
Symbol
FAM59B
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Family with sequence similarity 59, member B
NCBI Organism
Homo sapiens
Background Reference 01
Blagoev B, Ong SE, Kratchmarova I, et al. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat. Biotechnol.2004; 22:1139-45.
Background Reference 02
Tashiro K, Tsunematsu T, Okubo H, et al. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through activation of extracellular signal-regulated kinase signaling. J. Biol. Chem.2009; 284:20206-14.
Other Product Names
FAM59B Antibody: FAM59B, FAM59B, KIAA2038, HRIHFB2063, GRB2-associated and regulator of MAPK protein-like, GRB2-associated and regulator of MAPK1-like
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
190359325
Physical Properties
Liquid
Available Sizes
Curated Selection
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