What is the catalog number for SRPX2 Antibody?

The catalog number for SRPX2 Antibody is 5475.

What sizes are available for SRPX2 Antibody?

SRPX2 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does SRPX2 Antibody come in?

SRPX2 Antibody is available in 2 different pack sizes.

Is SRPX2 Antibody in stock?

SRPX2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

SRPX2 Antibody

Product Specifications

Background

SRPX2 Antibody: Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

NCBI Gene ID

27286

Swiss Prot

O60687

Accession Number

NP_055282

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

SRPX2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1302 - Human Lung Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Buffer

SRPX2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SRPX2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

SRPX2

Positive Control 2

Cat. No. 10-101 - Human Lung Tissue Slide

NCBI Official Name

Sushi-repeat-containing protein, X-linked 2

NCBI Organism

Homo sapiens

Background Reference 01

Roll P, Rudolf G, Pereira S, et al. SRPX2 mutations in disorders of language cortex and cognition. Hum. Mol. Genet.2006; 15:1195-207.

Background Reference 02

Miljkovic-Licina M, Hammel P, Garrido-Urbani S, et al. Sushi repeat protein X-linked 2, a novel mediator of angiogenesis. FASEB J.2009; 23:4105-16.

Background Reference 03

Blasi F and Carmeliet P. uPAR: a versatile signalling orchestrator. Nat. Rev. Mol. Cell. Biol.2002; 3:932-43.

Background Reference 04

Tanaka K, Arao T, Maegawa M, et al. SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion. Int. J. Cancer2009; 124:1072-80.