What is the catalog number for SRPX1 Antibody?

The catalog number for SRPX1 Antibody is 5473.

What sizes are available for SRPX1 Antibody?

SRPX1 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does SRPX1 Antibody come in?

SRPX1 Antibody is available in 2 different pack sizes.

Is SRPX1 Antibody in stock?

SRPX1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

SRPX1 Antibody

Product Specifications

Background

SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

NCBI Gene ID

8406

Swiss Prot

P78539

Accession Number

NP_006298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Autophagy

Purification

SRPX1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1220 - SK-N-SH Cell Lysate

Concentration

1 mg/mL

Buffer

SRPX1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SRPX1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

SRPX

Positive Control 2

Cat. No. 10-301 - Human Brain Tissue Slide

NCBI Official Name

Sushi-repeat-containing protein, X-linked

NCBI Organism

Homo sapiens

Background Reference 01

Dry KL, Aldred MA, Edgar AJ, et al. Identification of a novel gene, ETX1 from Xp21.1, a candidate gene for X-linked retinitis pigmentosa (RP3) . Hum. Mol. Genet.1995; 4:2347-53.