Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SRPX1 Antibody

Product Specifications

Background

SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

NCBI Gene ID

8406

Swiss Prot

P78539

Accession Number

NP_006298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Autophagy

Purification

SRPX1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1220 - SK-N-SH Cell Lysate

Concentration

1 mg/mL

Buffer

SRPX1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SRPX1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=5473

Fragment

IgG

Symbol

SRPX

Positive Control 2

Cat. No. 10-301 - Human Brain Tissue Slide

NCBI Official Name

Sushi-repeat-containing protein, X-linked

NCBI Organism

Homo sapiens

Background Reference 01

Dry KL, Aldred MA, Edgar AJ, et al. Identification of a novel gene, ETX1 from Xp21.1, a candidate gene for X-linked retinitis pigmentosa (RP3) . Hum. Mol. Genet.1995; 4:2347-53.

Background Reference 02

Iragavarapu S, Algeciras ME, Lee RK, et al. ETX1 is over-expressed in the glaucomatous trabecular meshwork. Mol. Vision2009; 15:2061-7.

Background Reference 03

Shimakage M, Kawahara K, Kikkawa N, et al. Downregulation of drs mRNA in human colon adenocarcinomas. Int. J. Cancer2000; 87:5-11.

Background Reference 04

Tambe Y, Isono T, Haraguchi S, et al. A novel apoptotic pathway induced by the drs tumor suppressor gene. Oncogene2004; 23:2977-87.

Other Product Names

SRPX1 Antibody: DRS, ETX1, SRPX1, HEL-S-83p, Sushi repeat-containing protein SRPX

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

5454086

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TRMT12 Mouse Monoclonal Antibody [Clone ID: LBI5C9]
AMM19077V 100 µL

TRMT12 Mouse Monoclonal Antibody [Clone ID: LBI5C9]

Ask
View Details
Human Liver Sinusoidal Endothelial Cells
ALHE11 1ml frozen Vial

Human Liver Sinusoidal Endothelial Cells

Ask
View Details
STK11IP (NM_052902) Human Tagged ORF Clone
RG205504 10 µg

STK11IP (NM_052902) Human Tagged ORF Clone

Ask
View Details
Anti-PDE1C Antibody, Rabbit Polyclonal
MBS8107016-01 0.1 mL

Anti-PDE1C Antibody, Rabbit Polyclonal

Ask
View Details
Anti-PDE1C Antibody, Rabbit Polyclonal
MBS8107016-02 5x 0.1 mL

Anti-PDE1C Antibody, Rabbit Polyclonal

Ask
View Details
Rabbit Anti-NG2 antibody
SL23787R-01 50 µL

Rabbit Anti-NG2 antibody

Ask
View Details