SLAIN2 Antibody
Product Specifications
Background
SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
NCBI Gene ID
57606
Swiss Prot
Q9P270
Accession Number
AAH40993
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
SLAIN2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 11-701 - Human Testis Tissue Slide
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (93%)
Buffer
SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SLAIN2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5471
Calculated Molecular Weight
64 kDa
Fragment
IgG
Specificity
SLAIN2 antibody is predicted not to cross-react with SLAIN1.
Symbol
SLAIN2
NCBI Official Name
SLAIN motif family, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.
Background Reference 02
Van der Vaart B, Manatschal C, Grigoriev I, et al. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J. Cell Biol. 2011; 193:1083-99.
Other Product Names
SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2
Tested Applications
ELISA, IHC-P
Protein ID
26454712
Physical Properties
Liquid
Available Sizes
Curated Selection
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