PGCC1 Antibody
Product Specifications
Background
PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
NCBI Gene ID
84498
Swiss Prot
Q96EK7
Accession Number
Q96EK7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
PGCC1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1471 - Rat Thymus Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (92%)
Buffer
PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
PGCC1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=5309
Fragment
IgG
Specificity
This antibody will not cross-react with FAM120A.
Symbol
FAM120B
NCBI Official Name
Family with sequence similarity 120B
NCBI Organism
Homo sapiens
Background Reference 01
Berger J and Moller DE. The mechanisms of actions of PPARs. Annu. Rev. Med.2002; 53:409-35.
Background Reference 02
Li D, Kang Q, and Wang D-M. Constitutive coactivator of peroxisome proliferator-activated receptor (PPARg), a novel coactivator of PPARg that promotes adipogenesis. Mol. Endocrin.2007; 21:2320-33.
Background Reference 03
Holden S and Raymond FL. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Gene2003; 318:149-61.
Other Product Names
PGCC1 Antibody: CCPG, PGCC1, KIAA1838, dJ894D12.1, CCPG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, PPARG constitutive coactivator 1, Constitutive coactivator of PPAR-gamma
Tested Applications
ELISA, WB
Protein ID
74751843
Physical Properties
Liquid
Available Sizes
Curated Selection
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