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TWA1 Antibody

Product Specifications

Background

TWA1 Antibody: TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.

NCBI Gene ID

54994

Swiss Prot

Q9NWU2

Accession Number

NP_060366

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

TWA1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1303 - Human Brain Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Chicken: (100%), Bovine: (100%)

Buffer

TWA1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TWA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=5305

Fragment

IgG

Symbol

GID8

NCBI Official Name

Chromosome 20 open reading frame 11

NCBI Organism

Homo sapiens

Background Reference 01

Umeda M, Nishitani H, and Nishimoto T. A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM. Gene2003; 303:47-54.

Background Reference 02

Kobayashi N, Yang J, Ueda A, et al. RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex. Gene2007; 396:236-47.

Other Product Names

TWA1 Antibody: TWA1, C20orf11, Glucose-induced degradation protein 8 homolog, Two hybrid-associated protein 1 with RanBPM, Twa1

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

8923557

Physical Properties

Liquid

Available Sizes

Curated Selection

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