Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

OCLN Antibody

Product Specifications

Background

OCLN Antibody: Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.

NCBI Gene ID

4950

Swiss Prot

Q16625

Accession Number

AAH29886

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

OCLN Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1304 - Human Liver Tissue Lysate

Concentration

1 mg/mL

Buffer

OCLN Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

OCLN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=5191

Fragment

IgG

Specificity

At least three isoforms of OCLN are known to exist.

Symbol

OCLN

Positive Control 2

Cat. No. 10-201 - Human Liver Tissue Slide

NCBI Official Name

Occludin

NCBI Organism

Homo sapiens

Background Reference 01

Tsukita S, Furuse M, and Itoh M. Multifunctional strands in tight junctions. Nat. Rev. Mol. Cell Biol. 2001; 2:285-93.

Background Reference 02

Chiba H, Osanai M, Murata M, et al. Transmembrane proteins of tight junctions. Biochim. Biophys. Acta 2008; 1778:588-600.

Background Reference 03

Furuse M, Hirase T, Itoh M, et al. Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol.1993; 1777-88.

Background Reference 04

Matter K, Aijaz S, Tsapara A, et al. Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Curr. Opin. Cell Biol. 2005; 17:453-8.

Other Product Names

OCLN Antibody: BLCPMG, Occludin

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

20987418

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

IL5 protein (Mouse)
30R-AI145 25 ug

IL5 protein (Mouse)

Ask
View Details
SMIM15 (NM_001048249) Human Over-expression Lysate
LS643155 100 µg

SMIM15 (NM_001048249) Human Over-expression Lysate

Ask
View Details
RPL24P7 CRISPR Knock Out 293T Cell Line (Human)
41229141 1x10<sup>6</sup> cells/1.0ml

RPL24P7 CRISPR Knock Out 293T Cell Line (Human)

Ask
View Details
FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)
MBS2077764-01 0.1 mL

FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)

Ask
View Details
FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)
MBS2077764-02 0.2 mL

FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)

Ask
View Details
FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)
MBS2077764-03 0.5 mL

FITC-Linked Polyclonal Antibody to Absent In Melanoma 2 (AIM2)

Ask
View Details