PTER Antibody

Product Specifications

Background

PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.

NCBI Gene ID

9317

Swiss Prot

Q96BW5

Accession Number

CAH73146

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity

Purification

PTER Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1305 - Human Kidney Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (88%)

Buffer

PTER Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

PTER antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

PTER

NCBI Official Name

Phosphotriesterase related

NCBI Organism

Homo sapiens

Background Reference 01

Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82.

Background Reference 02

Alimova-Kost MV, Imreh S, Buchman VL, et al. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet.. Cell Genet.1998; 83:16-7.

Background Reference 03

Meyre D, Delplanque J, Chevre JC, et al. Genome-wide associated study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet.2009; 41:157-9.