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ApoA1 Antibody

Product Specifications

Background

ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.

NCBI Gene ID

335

Swiss Prot

P02647

Accession Number

P02647

Host

Chicken

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

ApoA1 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1304 - Human Liver Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Pig: (83%), Bovine: (78%), Chicken: (71%)

Buffer

ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ApoA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgY

Symbol

APOA1

Positive Control 2

Cat. No. 10-201 - Human Liver Tissue Slide

NCBI Official Name

Apolipoprotein A-I

NCBI Organism

Homo sapiens

Background Reference 01

Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res.1989; 30:1397-403.

Background Reference 02

Lai C-Q, Parnell LD, and Ordovas JM. The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid.2005; 16:153-66.

Other Product Names

ApoA1 Antibody: Apolipoprotein A-I, Apolipoprotein A1, Apo-AI

Tested Applications

ELISA, WB, IF

Protein ID

113992

Physical Properties

Liquid

Available Sizes

Frequently Asked Questions

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