What is the catalog number for IL-17 Antibody?

The catalog number for IL-17 Antibody is 4887.

What sizes are available for IL-17 Antibody?

IL-17 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does IL-17 Antibody come in?

IL-17 Antibody is available in 2 different pack sizes.

Is IL-17 Antibody in stock?

IL-17 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

IL-17 Antibody

Product Specifications

Background

IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

NCBI Gene ID

3605

Swiss Prot

Q16552

Accession Number

NP_002181

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

4887

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Recombinant Protein Test (Figure 1) : Anit-IL-17 antibodies (4887) detected human IL-17 recombinant protein at different concentrations Recombinant Protein Test4887

Field of Research

Signal Transduction

Purification

IL-17 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 17-208 - A20 Cell Slide

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (84%), Rat: (81%), Pig: (74%)

Buffer

IL-17 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-17 antibody can be stored at 4˚ C for up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Isoform

Human IL-17 has only one isoform (155aa, 17.5kD) . Mouse IL-17 has one isoform (158aa, 17.5kD) and Rat IL-17 also has one isoform (150aa, 16.9kD) . 4887 can detect human, mouse and rat IL-17.