What is the catalog number for MED4 Antibody?

The catalog number for MED4 Antibody is 4729.

What sizes are available for MED4 Antibody?

MED4 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does MED4 Antibody come in?

MED4 Antibody is available in 2 different pack sizes.

Is MED4 Antibody in stock?

MED4 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MED4 Antibody

Product Specifications

Background

MED4 Antibody: The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment.

NCBI Gene ID

29079

Swiss Prot

Q9NPJ6

Accession Number

NP_054885

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease

Purification

MED4 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1313 - Human Testis Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (86%)

Buffer

MED4 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MED4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least three isoforms of MED4 are known to exist; this antibody only recognizes the largest isoform.

Symbol

MED4

Positive Control 2

Cat. No. 11-701 - Human Testis Tissue Slide

NCBI Official Name

Mediator complex subunit 4

NCBI Organism

Homo sapiens

Background Reference 01

Sato S, Tomomori-Sato C, Parmely TJ, et al. A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Mol. Cell2004; 14:685-91.

Background Reference 02

Gustafsson CM, Myers LC, Beve J, et al. Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae. J. Biol. Chem.1998; 273:30851-4.

Background Reference 03

Rachez C, Lemon BD, Suldan Z, et al. Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature1999; 398:824-8.

Background Reference 04

Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.

Other Product Names

MED4 Antibody: ARC36, VDRIP, DRIP36, TRAP36, HSPC126, ARC36, Mediator of RNA polymerase II transcription subunit 4, Activator-recruited cofactor 36 kDa component