RGPD5 Antibody
Product Specifications
Background
RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
NCBI Gene ID
84220
Swiss Prot
Q99666
Accession Number
NP_005045
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
RGPD5 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1314 - Human Thymus Tissue Lysate
Concentration
1 mg/mL
Buffer
RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RGPD5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=4585
Fragment
IgG
Symbol
RGPD5
Positive Control 2
Cat. No. 11-701 - Human Testis Tissue Slide
NCBI Official Name
RANBP2-like and GRIP domain containing 5
NCBI Organism
Homo sapiens
Background Reference 01
Nothwang HG, Rensing C, Kubler M, et al. Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on chromosome 2q11-q12. Genomics1998; 47:383-92.
Background Reference 02
Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.
Background Reference 03
Wang LF, Zhu HD, Miao SY, et al. Molecular cloning and characterization of a novel testis-specific nucleoporin-related gene. Arch. Androl.1999; 42:71-84.
Other Product Names
RGPD5 Antibody: BS63, RGP5, BS-63, HEL161, RANBP2L1, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, Sperm membrane protein BS-63, RanBP2L1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
83267877
Physical Properties
Liquid
Available Sizes
Curated Selection
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