Unc93a Antibody
Product Specifications
Background
Unc93a Antibody: Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.
NCBI Gene ID
54346
Swiss Prot
Q86WB7
Accession Number
AAH99718
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
Unc93a Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Buffer
Unc93a Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Unc93a antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=4551
Fragment
IgG
Specificity
Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.
Symbol
UNC93A
NCBI Official Name
Unc-93 homolog A (C. elegans)
NCBI Organism
Homo sapiens
Background Reference 01
Liu Y, Dodds P, Emilion G, et al. The human homolog of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. BioMed Central Genetics2002; 3:20.
Background Reference 02
Massey DC and Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy2007; 3:649-51.
Other Product Names
Unc93a Antibody: Unc-93A, dJ366N23.1, dJ366N23.2, Protein unc-93 homolog A, HmUnc-93A
Tested Applications
ELISA, WB
Protein ID
71043465
Physical Properties
Liquid
Available Sizes
Curated Selection
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