Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TRPC6 Antibody

Product Specifications

Background

TRPC6 Antibody: The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. When expressed in transfected cells, TRPC6 acts as a non-selective store-independent receptor-activated cation channel. It is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation. There is increasing evidence that TRPC6 encodes endogenous DAG-activated receptor-operated cation channels in vivo.

NCBI Gene ID

7225

Swiss Prot

Q9Y210

Accession Number

AAH93658

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Neuroscience

Purification

TRPC6 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1402 - Mouse Lung Tissue Lysate

Concentration

1 mg/mL

Buffer

TRPC6 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TRPC6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=3897

Fragment

IgG

Specificity

This antibody may cross-react with TRPC3.

Symbol

TRPC6

NCBI Official Name

Transient receptor potential cation channel, subfamily C, member 6

NCBI Organism

Homo sapiens

Background Reference 01

Contell C, Birnbaumer V, Flockerzi V, et al. A unified nomenclature for the superfamily of TRP cation channels. Mol. Cell 2002; 9:229-31.

Background Reference 02

Dietrich A, Kalwa H, Rost BR, et al. The diacylglycerol-sensitive TRPC6/6/7 subfamily of cation channels: functional characterization and physiological relevance. Pflugers Arch. 2005; 451:72-80.

Background Reference 03

Trebak M, Vazquez G, Bird GSJ, et al. The TRPC6/6/7 subfamily of cation channels. Cell Calcium 2003; 33:451-61

Other Product Names

TRPC6 Antibody: TRP6, FSGS2, TRP6, Short transient receptor potential channel 6, Transient receptor protein 6, TrpC6

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

62739910

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FUS Polyclonal Antibody, Biotin Conjugated
A51452-050 50 µL

FUS Polyclonal Antibody, Biotin Conjugated

Ask
View Details
EIF4G1 (NM_198244) Human Tagged ORF Clone
RG219966 10 µg

EIF4G1 (NM_198244) Human Tagged ORF Clone

Ask
View Details
Dual-Thickness MicroLoops; box of 20 with 800 micron aperture loops; mounted on 18 mm rods
M5-L18SP-800 20 Mounts

Dual-Thickness MicroLoops; box of 20 with 800 micron aperture loops; mounted on 18 mm rods

Ask
View Details
Thermal Cycler BTHC-409
BTHC-409 Each

Thermal Cycler BTHC-409

Ask
View Details
RS09 2TFA (1449566-36-2 free base)
TP1938L-01 10mg

RS09 2TFA (1449566-36-2 free base)

Ask
View Details
RS09 2TFA (1449566-36-2 free base)
TP1938L-02 1g

RS09 2TFA (1449566-36-2 free base)

Ask
View Details