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CTRP3 Antibody

Product Specifications

Background

CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.

NCBI Gene ID

114899

Swiss Prot

Q9BXJ4

Accession Number

NP_852100

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

3565

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Recombinant Protein Test (Figure 2) : Anti-CTRP3 antibodies (3565) detected human CTRP3 recombinant protein. Recombinant Protein Test3565

Field of Research

Signal Transduction

Purification

CTRP3 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1401 - Mouse Heart Tissue Lysate

Concentration

1 mg/mL

Buffer

CTRP3 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CTRP3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=3565

Fragment

IgG

Specificity

Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.

Isoform

Human CTRP3 has 3 isoforms, including isoform 1 (246aa, 27kD), isoform 2 (198aa, 22kD) and isoform 3 (319aa, 35kD) . Mouse CTRP3 has one isoform (246aa, 27kD) and Rat CTRP3 also has one isoform (319aa, 35kD) . 3565 can detect human, mouse and rat.

Symbol

C1QTNF3

Positive Control 2

Cat. No. 1203 - A549 Cell Lysate

Positive Control 3

Cat. No. 1205 - Jurkat Cell Lysate

Positive Control 4

Cat. No. 1282 - 3T3/NIH Cell Lysate

NCBI Official Name

C1q and tumor necrosis factor related protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Fantuzzi. J. Allergy Clin. Immunol. 2005; 115:911-9.

Background Reference 02

Tsao et al. Euro. J. Pharmacol. 2002; 440:213-21.

Background Reference 03

Wong et al. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.

Background Reference 04

Shapiro and Scherer. Curr. Biol. 1998; 8:335-8.

Other Product Names

CTRP3 Antibody: CORS, CORCS, CTRP3, CORS26, C1ATNF3, CORS-26, UNQ753/PRO1484, Complement C1q tumor necrosis factor-related protein 3, Collagenous repeat-containing sequence 26 kDa protein

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

62739183

Physical Properties

Liquid

Available Sizes

Curated Selection

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