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SARS-CoV-2 (COVID-19) Envelope Antibody

Product Specifications

Background

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Envelope protein is a small polypeptide that contains at least one alpha-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic coronavirus E proteins, and also viral replication (3) .

NCBI Gene ID

43740570

Swiss Prot

QHD43418

Accession Number

QHD43418

Host

Rabbit

Reactivity

Virus

Immunogen

3531

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (100%)

Buffer

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=3531

Fragment

IgG

Isoform

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope has one isoform (75aa) .

Symbol

E

NCBI Official Name

Envelope protein

NCBI Organism

Wuhan seafood market pneumonia virus

Background Reference 01

Gorbalenya. bioRxiv: 2020.

Background Reference 02

Hui et al. Int J Infect Dis. 2020;91:264-266.

Background Reference 03

Pervushin et al. PLoS Pathog. 2009; 5 (7) : e1000511.

Citation 01

32659620

Citation 02

32779733

Citation 03

32805515

Citation 04

32895985

Citation 05

33058948

Citation 06

32779733

Citation 07

32387855

Citation 08

32844243

Other Product Names

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Envelope protein, E protein

Tested Applications

ELISA, IHC, IF

Protein ID

1791269092

Physical Properties

Liquid

Available Sizes

Curated Selection

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