What is the catalog number for MD-2 Antibody?

The catalog number for MD-2 Antibody is 3289.

What sizes are available for MD-2 Antibody?

MD-2 Antibody is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does MD-2 Antibody come in?

MD-2 Antibody is available in 2 different pack sizes.

Is MD-2 Antibody in stock?

MD-2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

MD-2 Antibody

Product Specifications

Background

MD-2 Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) . TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

NCBI Gene ID

23643

Swiss Prot

Q9Y6Y9

Accession Number

NP_056179

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

3289

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Recombinant Protein Test (Figure 1) : Anti-MD-2 antibodies (3289) detected human MD-2 recombinant protein at different concentrations. Recombinant Protein Test3289

Field of Research

Innate Immunity

Purification

MD-2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1406 - Mouse Spleen Tissue Lysate

Concentration

1 mg/mL

Buffer

MD-2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MD-2 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Isoform

Human MD-2 has 2 isoforms, including isoform 1 (160aa, 18kD) and isoform 2 (130aa, 15kD) . Mouse MD-2 has one isoform (160aa, 18kD) and Rat MD-2 also has one isoform (160aa, 18kD) . 3289 can detect human, mouse and rat.