ACE2 Antibody

Product Specifications

Background

COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans

NCBI Gene ID

59272

Swiss Prot

Q9BYF1

Accession Number

NP_068576

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease

Purification

ACE2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1305 - Human Kidney Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (93%)

Buffer

ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ACE2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

Anti-ACE2 has no cross response to ACE1.

Isoform

Human ACE2 has 2 isoforms, including isoform 1 (805aa, 93kD) and isoform 2 (555aa, 64kD) . Mouse ACE2 also has 2 isoforms, including isoform 1 (805aa, 92kD) and isoform 2 (353aa, 40kD) . Rat ACE2 has one isoform (805aa, 93kD) . 3229 can detect human, mouse and rat.

Symbol

ACE2

Positive Control 2

Cat. No. 10-401 - Human Kidney Tissue Slide

NCBI Official Name

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

NCBI Organism

Homo sapiens

Background Reference 01

Donoghue et al. Circ. Res. 2000;87:1-9.

Background Reference 02

Tipnis et al. J Biol. Chem. 2000;275:33238-43.

Background Reference 03

Li et al. Nature 2003;426:450-4.

Background Reference 04

Lu et al. The Lancet 2020 (published online) .

Background Reference 05

Crackower et al. Nature 2002;417:822-8.

Other Product Names

ACE2 Antibody: ACEH, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, ACEH, SARS-CoV receptor, SARS-CoV-2 receptor

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

11225609

Physical Properties

Liquid

Available Sizes

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