SARS-CoV Spike Antibody

Product Specifications

Background

SARS-CoV Spike Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome) . Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.

NCBI Gene ID

1489668

Swiss Prot

P59594

Accession Number

P59594

Host

Rabbit

Reactivity

Virus

Immunogen

3221

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV Spike Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 56%, homology 69%)

Buffer

SARS-CoV Spike Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV Spike antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Applications Notes

SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 2 ng of free peptide at 1 μ g/mL.

Isoform

SARS-CoV Spike has one isoform (1255aa) .

Symbol

NCBI Official Name

Spike glycoprotein

NCBI Organism

SARS coronavirus

Background Reference 01

Marra et al. Science 2003;300:1399-404.

Background Reference 02

Rota et al. Science 2003;300:1394-9.

Background Reference 03

Navas-Nartin et al. J Neurovirol. 2004;10:75-85.

Background Reference 04

Li et al. Nature 2003;426:450-4.

Other Product Names

SARS-CoV Spike Antibody: E2, Spike glycoprotein, E2, S glycoprotein

Tested Applications

ELISA

Protein ID

30173397

Physical Properties

Liquid

Available Sizes

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