ACE2 Antibody

Product Specifications

Background

COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans

NCBI Gene ID

59272

Swiss Prot

Q9BYF1

Accession Number

NP_068576

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

3217

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Independent Antibody Validation in Cell lines (Figure 1) shows similar ACE2 expression profile in human cell lines detected by three independent anti-ACE2 antibodies that recognize different epitopes, 3215 against central domain, 3217 against C-terminus domain and 3227 against N-terminus domain. ACE2 proteins are detected in the most tested tissues at different expression levels by three independent antibodies. Independent Antibody Validation in Cell lines3215 32173227

Field of Research

Infectious Disease

Purification

ACE2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1305 - Human Kidney Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Bovine: (88%)

Buffer

ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ACE2 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

Anti-ACE2 has no cross response to ACE1.

Isoform

Human ACE2 has 2 isoforms, including isoform 1 (805aa, 93kD) and isoform 2 (555aa, 64kD) . Mouse ACE2 also has 2 isoforms, including isoform 1 (805aa, 92kD) and isoform 2 (353aa, 40kD) . Rat ACE2 has one isoform (805aa, 93kD) . 3215 can detect human, mouse and rat.