CARD9 Antibody
Product Specifications
Background
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κ B. CARD9 is an upstream activator of BCL-10 and NF-κ B signaling.
NCBI Gene ID
64170
Swiss Prot
Q9H257
Accession Number
AF311287
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
CARD9 Antibody is DEAE purified.
Positive Control
Cat. No. 1216 - PC-3 Cell Lysate
Concentration
1 mg/ml
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (88%), Rat: (82%)
Buffer
CARD9 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CARD9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=2515
Calculated Molecular Weight
59 kDa
Fragment
IgG
Symbol
CARD9
Positive Control 2
Cat. No. 1217 - MDA-MB-361 Cell Lysate
Positive Control 3
Cat. No. 1204 - K562 Cell Lysate
Positive Control 4
Cat. No. 17-004 - K-562 Cell Slide
NCBI Official Name
Caspase recruitment domain family, member 9
NCBI Organism
Homo sapiens
Background Reference 01
Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κ B. J Biol Chem. 2000;275 (52) :41082-6. (RD0202)
Other Product Names
CARD9 Antibody: CANDF2, hCARD9, Caspase recruitment domain-containing protein 9
Tested Applications
ELISA, WB, ICC
Protein ID
11066983
Physical Properties
Liquid
Available Sizes
Curated Selection
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