GPT (ALT)

The enzyme alanine aminotransferase (ALT) or glutamate pyruvate transaminase (GPT) is widely reported in a variety of tissue sources. The major source of ALT is of hepatic origin and has led to the application of ALT determinations to the study of hepatic diseases. Elevated serum levels are found in hepatitis, cirrhosis and obstructive jaundice. When ALT is determined together with GOT (AST), in case of myocardial infarcts, the ALT levels will stay within the normal limits or only be slightly elevated in comparison to highly elevated AST levels.