CD40L/CD154/TRAP, Canine (HEK293, Fc)
Selected Variant
HY-P75406
Size: 1 Each
CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in Canine, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3) . CD40L/CD154/TRAP Protein, Canine (HEK293, Fc) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal mFc-tag.
Product Specifications
Product Name Alternative
CD40L/CD154/TRAP Protein, Canine (HEK293, Fc), Canine, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/cd40l-cd154-trap-protein-canine-hek293-fc.html
Molecular Formula
403468 (Gene_ID) O97626 (M112-L260) (Accession)
Molecular Weight
Approximately 47 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Price
Frequently Asked Questions
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