Nirvanol

Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the maximal electroshock (M.E.S.) seizure model in mice. Nirvanol shows potential for research in epilepsy-related neurological disorders[1].

Product Specifications

CAS Number

[631-07-2]

Product Name Alternative

Ethylphenylhydantoin; Phenylethyihydantoin; Desmethylmephenytoin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nirvanol.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC(C(C2=CC=CC=C2)(CC)N1)=O

Molecular Formula

C11H12N2O2

Molecular Weight

204.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Kupferberg HJ, et al. The metabolism of 3-methyl-5-ethyl-5-phenylhydantoin (mephenytoin) to 5-ethyl-5-phenylhydantoin (Nirvanol) in mice in relation to anticonvulsant activity. Drug Metab Dispos. 1975 Jan-Feb;3 (1) :26-9. PMID: 234831.