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Hbb (BC032264) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a beta polypeptide chain found in adult hemoglobin, which consists of a tetramer of two alpha chains and two beta chains, and which functions in the transport of oxygen to various peripheral tissues. This gene is one of a cluster of beta-hemoglobin genes that are distally regulated by a locus control region, and which are organized along the chromosome in the order of their developmental expression. In mouse, two major strain-specific haplotypes of the beta-globin gene cluster are found - a "single" haplotype found in C57BL/-type strains, which includes two highly similar adult beta-globin genes, beta s and beta t, and a "diffuse" haplotype found in strains such as BALB/c and 129Sv, which includes two somewhat diverse adult beta-globin genes, beta-major and beta-minor. This gene represents the beta-minor adult gene found in the "diffuse" haplotype. Primary chromosome 7 of the mouse reference genome assembly, which is derived from C57BL/6 strain mice, represents the "single" haplotype, while the "diffuse" haplotype is represented in the reference genome collection by the BALB/c strain alternate contig, NT_095534.1. [provided by RefSeq, May 2013]

Overview

Purified recombinant protein of Mouse hemoglobin, beta adult minor chain, (cDNA clone MGC:40691 IMAGE:3988455) full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI036344; beta2; Hbb2; Hbbt2

Gene ID

15130

UniProt

P02089

Accession Number mRNA

BC032264

Chromosomal Location

7 54.85 cM

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

23.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Hbb

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/15130

Uniprot URL

https://www.uniprot.org/uniprot/P02089

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC032264

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