Aif1 (NM_019467) Mouse Recombinant Protein

Product Specifications

Background

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse allograft inflammatory factor 1 (Aif1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI607846; AIF-1; D17H6S50E; G1; Iba1

Gene ID

11629

UniProt

O70200, Q4FJL9

Accession Number mRNA

NM_019467

Chromosomal Location

17 18.59 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

16.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.