Gfer (NM_023040) Mouse Recombinant Protein
Product Specifications
Background
FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse growth factor, augmenter of liver regeneration (Gfer), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Alr; ERV1
Gene ID
11692
UniProt
P56213
Accession Number mRNA
NM_023040
Chromosomal Location
17 12.48 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
22.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gfer
Species
Mouse
Protein ID
NP_075527
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11692
Uniprot URL
https://www.uniprot.org/uniprot/P56213
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023040
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075527
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