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Slc9a3r1 (NM_012030) Mouse Recombinant Protein

Product Specifications

Background

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling (By similarity) . May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules (By similarity) . Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.[UniProtKB/Swiss-Prot Function]

Synonyms

EBP-50; NHE-RF; NHERF-1; NHERF1

Gene ID

26941

UniProt

P70441, Q3TG37

Accession Number mRNA

NM_012030

Chromosomal Location

11 E2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

38.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Slc9a3r1

Species

Mouse

Protein ID

NP_036160

Overview

Purified recombinant protein of Mouse solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/26941

Uniprot URL

https://www.uniprot.org/uniprot/P70441

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012030

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036160

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