Mfn1 (NM_024200) Mouse Recombinant Protein

Product Specifications

Background

Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672) . Membrane clustering requires GTPase activity (By similarity) . It may involve a major rearrangement of the coiled coil domains (PubMed:15297672) . Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753) . Overexpression induces the formation of mitochondrial networks (in vitro) . Has low GTPase activity (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse mitofusin 1 (Mfn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2310002F04Rik; 6330416C07Rik; D3Ertd265e; HR2; mKIAA4032

Gene ID

67414

UniProt

Q811U4

Accession Number mRNA

NM_024200

Chromosomal Location

3 15.75 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

83.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.