Atp2a1 (NM_007504) Mouse Recombinant Protein
Product Specifications
Background
Key regulator of striated muscle performance by acting as the major Ca (2+) ATPase responsible for the reuptake of cytosolic Ca (2+) into the sarcoplasmic reticulum (PubMed:21697544, PubMed:22961106, PubMed:25640239, PubMed:26816378) . Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:21697544, PubMed:22961106, PubMed:25640239, PubMed:26816378) .[UniProtKB/Swiss-Prot Function]
Synonyms
SERCA1
Gene ID
11937
UniProt
Q8R429
Accession Number mRNA
NM_007504
Chromosomal Location
7 69.04 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
109.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Atp2a1
Species
Mouse
Protein ID
NP_031530
Overview
Purified recombinant protein of Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11937
Uniprot URL
https://www.uniprot.org/uniprot/Q8R429
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007504
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031530
Curated Selection
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