B4galt5 (NM_019835) Mouse Recombinant Protein

Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:21057870, PubMed:23882130, PubMed:30114188) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (PubMed:30114188) . Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (PubMed:29415997) . Essential for extraembryonic development during early embryogenesis (PubMed:20574042, PubMed:21057870) .[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Mouse UDP-Gal:betaGlcNAc beta 1, 4-galactosyltransferase, polypeptide 5 (B4galt5), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.