PPME1 (NM_016147) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Synonyms
ABDH19; PME-1
Gene ID
51400
UniProt
Q9Y570, A0A140VK39
Accession Number mRNA
NM_016147
Chromosomal Location
11q13.4
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
42.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPME1
Species
Human
Protein ID
NP_057231
Overview
Recombinant protein of human protein phosphatase methylesterase 1 (PPME1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51400
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y570
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016147
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057231
Curated Selection
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