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14 3 3 eta (YWHAH) (NM_003405) Human Recombinant Protein

Product Specifications

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

Synonyms

YWHA1

Gene ID

7533

UniProt

Q04917, A0A024R1K7, Q9H4N8

Accession Number mRNA

NM_003405

Chromosomal Location

22q12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

Field of Research

Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

28 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

YWHAH

Species

Human

Protein ID

NP_003396

Overview

Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7533

Uniprot URL

https://www.uniprot.org/uniprot/Q04917

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003405

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003396

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