14 3 3 eta (YWHAH) (NM_003405) Human Recombinant Protein
Product Specifications
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
Overview
Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH)
Synonyms
YWHA1
Gene ID
7533
UniProt
Q04917, A0A024R1K7, Q9H4N8
Accession Number mRNA
NM_003405
Chromosomal Location
22q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis
Field of Research
Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
28 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
YWHAH
Species
Human
Protein ID
NP_003396
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7533
Uniprot URL
https://www.uniprot.org/uniprot/Q04917
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003405
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003396
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