DBR1 (NM_016216) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]
Overview
Recombinant protein of human debranching enzyme homolog 1 (S. cerevisiae) (DBR1)
Synonyms
Debranching enzyme homolog 1; debranching enzyme homolog 1 (S. cerevisiae) ; RNA lariat debranching enzyme
Gene ID
51163
UniProt
Q9UK59
Accession Number mRNA
NM_016216
Chromosomal Location
3q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
61.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DBR1
Species
Human
Protein ID
NP_057300
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51163
Uniprot URL
https://www.uniprot.org/uniprot/Q9UK59
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016216
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057300
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