METTL9 (NM_016025) Human Recombinant Protein

Product Specifications

Background

Protein-histidine N-methyltransferase that specifically catalyzes 1-methylhistidine (pros-methylhistidine) methylation of target proteins (PubMed:33563959) . Mediates methylation of proteins with a His-x-His (HxH) motif (where 'x' is preferably a small amino acid) (PubMed:33563959) . Catalyzes methylation of target proteins such as S100A9, NDUFB3, SLC39A5, SLC39A7, ARMC6 and DNAJB12; 1-methylhistidine modification may affect the binding of zinc and other metals to its target proteins (PubMed:33563959) . Constitutes the main methyltransferase for the 1-methylhistidine modification in cell (PubMed:33563959) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human methyltransferase like 9 (METTL9), transcript variant 1

Synonyms

CGI-81; DREV; DREV1; PAP1

Gene ID

51108

UniProt

Q9H1A3

Accession Number mRNA

NM_016025

Chromosomal Location

16p12.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

36.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.