TMX2 (NM_015959) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
Synonyms
CGI-31; NEDMCMS; PDIA12; PIG26; TXNDC14
Gene ID
51075
UniProt
Q9Y320
Accession Number mRNA
NM_015959
Chromosomal Location
11q12.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
33.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TMX2
Species
Human
Protein ID
NP_057043
Overview
Recombinant protein of human thioredoxin-related transmembrane protein 2 (TMX2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51075
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y320
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015959
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057043
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