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Glutathione S Transferase theta 2 (GSTT2) (NM_000854) Human Recombinant Protein

Selected Variant

PH42271M5

Size: 20 µg

Product Specifications

Background

The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015]

Overview

Recombinant protein of human glutathione S-transferase theta 2 (GSTT2)

Synonyms

GSTT2B

Gene ID

2953

UniProt

P0CG29

Accession Number mRNA

NM_000854

Chromosomal Location

22q11.23

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

Field of Research

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

27.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GSTT2

Species

Human

Protein ID

NP_000845

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2953

Uniprot URL

https://www.uniprot.org/uniprot/P0CG29

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000854

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000845

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