DYNLRB1 (NM_014183) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]
Overview
Recombinant protein of human dynein, light chain, roadblock-type 1 (DYNLRB1)
Synonyms
BITH; BLP; DNCL2A; DNLC2A; ROBLD1
Gene ID
83658
UniProt
Q9NP97
Accession Number mRNA
NM_014183
Chromosomal Location
20q11.22
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
10.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DYNLRB1
Species
Human
Protein ID
NP_054902
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83658
Uniprot URL
https://www.uniprot.org/uniprot/Q9NP97
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014183
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_054902
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