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DYNLRB1 (NM_014183) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

Overview

Recombinant protein of human dynein, light chain, roadblock-type 1 (DYNLRB1)

Synonyms

BITH; BLP; DNCL2A; DNLC2A; ROBLD1

Gene ID

83658

UniProt

Q9NP97

Accession Number mRNA

NM_014183

Chromosomal Location

20q11.22

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

10.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DYNLRB1

Species

Human

Protein ID

NP_054902

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/83658

Uniprot URL

https://www.uniprot.org/uniprot/Q9NP97

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014183

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_054902

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