NFYC (NM_014223) Human Recombinant Protein
Product Specifications
Background
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Synonyms
CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC
Gene ID
4802
UniProt
Q13952
Accession Number mRNA
NM_014223
Chromosomal Location
1p34.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
37 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NFYC
Species
Human
Protein ID
NP_055038
Overview
Recombinant protein of human nuclear transcription factor Y, gamma (NFYC), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4802
Uniprot URL
https://www.uniprot.org/uniprot/Q13952
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014223
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055038
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