NFYC (NM_014223) Human Recombinant Protein

Product Specifications

Background

This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Overview

Recombinant protein of human nuclear transcription factor Y, gamma (NFYC), transcript variant 2

Synonyms

CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC

Gene ID

4802

UniProt

Q13952

Accession Number mRNA

NM_014223

Chromosomal Location

1p34.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Antigen processing and presentation

Field of Research

Antigen processing and presentation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

37 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.