C12orf11 (ASUN) (NM_018164) Human Recombinant Protein
Product Specifications
Background
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human chromosome 12 open reading frame 11 (C12orf11)
Synonyms
ASUN; C12orf11; GCT1; Mat89Bb; NET48; SPATA30
Gene ID
55726
UniProt
Q9NVM9
Accession Number mRNA
NM_018164
Chromosomal Location
12p11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
80 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
INTS13
Species
Human
Protein ID
NP_060634
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55726
Uniprot URL
https://www.uniprot.org/uniprot/Q9NVM9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018164
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060634
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