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GGA2 (NM_015044) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2)

Synonyms

VEAR

Gene ID

23062

UniProt

Q9UJY4

Accession Number mRNA

NM_015044

Chromosomal Location

16p12.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Lysosome

Field of Research

Lysosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

67 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GGA2

Species

Human

Protein ID

NP_055859

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23062

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJY4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015044

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055859

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