GGA2 (NM_015044) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2)
Synonyms
VEAR
Gene ID
23062
UniProt
Q9UJY4
Accession Number mRNA
NM_015044
Chromosomal Location
16p12.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Lysosome
Field of Research
Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
67 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GGA2
Species
Human
Protein ID
NP_055859
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23062
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJY4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015044
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055859
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