PIH1D1 (NM_017916) Human Recombinant Protein
Product Specifications
Background
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026) . Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451) . Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032) . Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human PIH1 domain containing 1 (PIH1D1)
Synonyms
MOT48; NOP17; Pih1
Gene ID
55011
UniProt
Q9NWS0
Accession Number mRNA
NM_017916
Chromosomal Location
19q13.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
32.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PIH1D1
Species
Human
Protein ID
NP_060386
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55011
Uniprot URL
https://www.uniprot.org/uniprot/Q9NWS0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017916
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060386
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