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PIH1D1 (NM_017916) Human Recombinant Protein

Product Specifications

Background

Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026) . Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451) . Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032) . Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human PIH1 domain containing 1 (PIH1D1)

Synonyms

MOT48; NOP17; Pih1

Gene ID

55011

UniProt

Q9NWS0

Accession Number mRNA

NM_017916

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

32.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PIH1D1

Species

Human

Protein ID

NP_060386

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55011

Uniprot URL

https://www.uniprot.org/uniprot/Q9NWS0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017916

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060386

Frequently Asked Questions

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